Catalpol Ameliorates Podocyte Injury by Stabilizing Cytoskeleton and Enhancing Autophagy in Diabetic Nephropathy

Catalpol, an iridoid glycoside extracted from Rehmannia glutinosa, has been found to ameliorate diabetic nephropathy (DN), but the mechanism has not been clarified. Podocyte injury play a key role in the pathogenesis of DN. This study mainly investigated the protective effect and potential mechanism...

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Vydáno v:Front Pharmacol
Hlavní autoři: Chen, Yan, Liu, Qingpu, Shan, Zengfu, Mi, Wangyang, Zhao, Yingying, Li, Meng, Wang, Baiyan, Zheng, Xiaoke, Feng, Weisheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914850/
https://ncbi.nlm.nih.gov/pubmed/31920663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01477
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