Data Integration Methods for Phenotype Harmonization in Multi-Cohort Genome-Wide Association Studies With Behavioral Outcomes

Parallel meta-analysis is a popular approach for increasing the power to detect genetic effects in genome-wide association studies across multiple cohorts. Consortia studying the genetics of behavioral phenotypes are oftentimes faced with systematic differences in phenotype measurement across cohort...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Luningham, Justin M., McArtor, Daniel B., Hendriks, Anne M., van Beijsterveldt, Catharina E. M., Lichtenstein, Paul, Lundström, Sebastian, Larsson, Henrik, Bartels, Meike, Boomsma, Dorret I., Lubke, Gitta H.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914843/
https://ncbi.nlm.nih.gov/pubmed/31921287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01227
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