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Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins

Many traits vary among isogenic individuals in homogeneous environments. In microbes, plants and animals, variation in the protein chaperone system affects many such traits. In the animal model C. elegans, the expression level of hsp-16.2 chaperone biomarkers correlates with or predicts the penetran...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Burnaevskiy, Nikolay, Sands, Bryan, Yun, Soo, Tedesco, Patricia M., Johnson, Thomas E., Kaeberlein, Matt, Brent, Roger, Mendenhall, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914778/
https://ncbi.nlm.nih.gov/pubmed/31844058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13664-7
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