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Despite early antiretroviral therapy effector memory and follicular helper CD4 T cells are major reservoirs in visceral lymphoid tissues of SIV-infected macaques

Whereas antiretroviral therapy (ART) suppresses viral replication, ART discontinuation results in viral rebound, indicating the presence of viral reservoirs (VRs) established within lymphoid tissues. Herein, by sorting CD4 T-cell subsets from the spleen, mesenteric and peripheral lymph nodes (LNs) o...

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Bibliografiske detaljer
Udgivet i:Mucosal Immunol
Main Authors: Rabezanahary, Henintsoa, Moukambi, Félicien, Palesch, David, Clain, Julien, Racine, Gina, Andreani, Guadalupe, Benmadid-Laktout, Ghita, Zghidi-Abouzid, Ouafa, Soundaramourty, Calayselvy, Tremblay, Cécile, Silvestri, Guido, Estaquier, Jérôme
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914669/
https://ncbi.nlm.nih.gov/pubmed/31723251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-019-0221-x
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