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Sensitized brain response to acute pain in patients using prescription opiates for chronic pain: A pilot study

BACKGROUND: Chronic opiate use leads to a sensitized behavioral response to acute pain, which in turn, leads to escalating doses of opiates. This study was designed to test the hypothesis that chronic opiate usage is also associated with a sensitized neurobiological response to acute pain in individ...

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Detalhes bibliográficos
Publicado no:Drug Alcohol Depend
Main Authors: Dowdle, Logan T., Borckardt, Jeffrey J., Back, Sudie E., Morgan, Katherine, Adams, David, Madan, Alok, Balliet, Wendy, Hanlon, Colleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6914256/
https://ncbi.nlm.nih.gov/pubmed/31071496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2019.02.024
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