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Mechanisms of and approaches to overcoming resistance to immunotherapy

Immunotherapies have been successfully developed for the treatment of B-cell acute lymphoblastic leukemia (B-ALL) with FDA approval of blinatumomab, inotuzumab, and tisagenlecleucel for relapsed or refractory patients. These agents target either CD19 or CD22, which are both expressed on the surface...

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Detalhes bibliográficos
Publicado no:Hematology Am Soc Hematol Educ Program
Main Authors: Schultz, Liora, Gardner, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913466/
https://ncbi.nlm.nih.gov/pubmed/31808880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/hematology.2019000018
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