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Identification of a novel MYOC variant in a Hispanic family with early-onset primary open-angle glaucoma with elevated intraocular pressure

Primary open-angle glaucoma (POAG) is the leading cause of irreversible blindness worldwide. Most cases are multifactorial in etiology, but some are associated with variants in the myocilin gene, MYOC. Here, we report the identification of a novel MYOC variant, c.1153G>A, in a 24-yr-old female pa...

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Publicado en:Cold Spring Harb Mol Case Stud
Autores principales: Criscione, June, Ji, Weizhen, Jeffries, Lauren, McGrath, James M., Soloway, Scott, Pusztai, Lajos, Lakhani, Saquib
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913140/
https://ncbi.nlm.nih.gov/pubmed/31653660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a004374
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