Enhancing the precision of genetic lineage tracing using dual recombinases

The Cre-loxP recombination system is the most widely used technology for in vivo tracing of stem or progenitor cell lineages. The precision of this genetic system largely depends on the specificity of Cre expression in targeted stem or progenitor cells. However, Cre expression in non-targeted cell t...

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Publicado en:Nat Med
Autores principales: He, Lingjuan, Li, Yan, Li, Yi, Pu, Wenjuan, Huang, Xiuzhen, Tian, Xueying, Wang, Yue, Zhang, Hui, Liu, Qiaozhen, Zhang, Libo, Zhao, Huan, Tang, Juan, Ji, Hongbin, Cai, Dongqing, Han, Zhibo, Han, Zhongchao, Nie, Yu, Hu, Shengshou, Wang, Qing-Dong, Sun, Ruilin, Fei, Jian, Wang, Fengchao, Chen, Ting, Yan, Yan, Huang, Hefeng, Pu, William T., Zhou, Bin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913096/
https://ncbi.nlm.nih.gov/pubmed/29131159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4437
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