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Maternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation

BACKGROUND: Coronary heart disease (CHD) is the most common cause of mortality globally, yet mitochondrial genetic mutations associated with CHD development remain incompletely understood. METHODS: The subjects from three Chinese families with LHON underwent clinical, genetic, molecular, and biochem...

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Detalhes bibliográficos
Publicado no:BMC Cardiovasc Disord
Main Authors: Zhang, Zhenxiao, Liu, Mingyang, He, Jianshuai, Zhang, Xiaotian, Chen, Yuehua, Li, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912950/
https://ncbi.nlm.nih.gov/pubmed/31842766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-019-01284-4
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