The effect of 5α-oleandrin on keloid fibroblast activities

BACKGROUND: Keloids develop due to hyperactivity of keloid fibroblast (KF) in proliferation, migration, and collagen deposition along with low rates of collagen degradation. These are a result of the Wnt/β catenin signaling pathways under stimulation of TGF-β. 5α-oleandrin can suppress Wnt-targeted...

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Detalhes bibliográficos
Publicado no:BMC Proc
Main Authors: Dachlan, Ishandono, Wirohadidjojo, Yohanes Widodo, Wahyuningsih, Mae Sri Hartati, Aryandono, Teguh, Soebono, Hardyanto, Afandy, Dwiki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912934/
https://ncbi.nlm.nih.gov/pubmed/31890007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12919-019-0177-6
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