Heavy Water (D(2)O) Containing Preservation Solution Reduces Hepatic Cold Preservation and Reperfusion Injury in an Isolated Perfused Rat Liver (IPRL) Model

Background: Heavy water (D(2)O) has many biological effects due to the isotope effect of deuterium. We previously reported the efficacy of D(2)O containing solution (Dsol) in the cold preservation of rat hearts. Here, we evaluated whether Dsol reduced hepatic cold preservation and reperfusion injury...

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Publicado en:J Clin Med
Main Authors: Shimada, Shingo, Fukai, Moto, Shibata, Kengo, Sakamoto, Sodai, Wakayama, Kenji, Ishikawa, Takahisa, Kawamura, Norio, Fujiyoshi, Masato, Shimamura, Tsuyoshi, Taketomi, Akinobu
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912838/
https://ncbi.nlm.nih.gov/pubmed/31683811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8111818
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