GSTM1 and Liver Iron Content in Children with Sickle Cell Anemia and Iron Overload

Chronic blood transfusions in patients with sickle cell anemia (SCA) cause iron overload, which occurs with a degree of interpatient variability in serum ferritin and liver iron content (LIC). Reasons for this variability are unclear and may be influenced by genes that regulate iron metabolism. We e...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Puri, Latika, Flanagan, Jonathan M., Kang, Guolian, Ding, Juan, Bi, Wenjian, McCarville, Beth M., Loeffler, Ralf B., Tipirneni-Sajja, Aaryani, Villavicencio, Martha, Crews, Kristine R., Hillenbrand, Claudia M., Hankins, Jane S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912836/
https://ncbi.nlm.nih.gov/pubmed/31694285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8111878
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