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Clusterin Attenuates Hepatic Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Downregulating the Smad3 Signaling Pathway

Clusterin is a glycoprotein that is expressed in most human tissues and found in body fluids. In our previous studies we demonstrated that clusterin has a protective effect against hepatic lipid accumulation and renal fibrosis; however, the role of clusterin in hepatic fibrosis is unknown. Here, we...

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Опубликовано в: :Cells
Главные авторы: Seo, Hye-Young, Lee, So-Hee, Lee, Ji-Ha, Kang, Yu Na, Choi, Young-Keun, Hwang, Jae Seok, Park, Keun-Gyu, Jang, Byoung Kuk, Kim, Mi Kyung
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912488/
https://ncbi.nlm.nih.gov/pubmed/31739636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111442
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