iPSCs-Based Neural 3D Systems: A Multidimensional Approach for Disease Modeling and Drug Discovery

Induced pluripotent stem cells (iPSCs)-based two-dimensional (2D) protocols have offered invaluable insights into the pathophysiology of neurological diseases. However, these systems are unable to reproduce complex cytoarchitectural features, cell-cell and tissue-tissue interactions like their in vi...

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Bibliographic Details
Published in:Cells
Main Authors: Costamagna, Gianluca, Andreoli, Luca, Corti, Stefania, Faravelli, Irene
Format: Artigo
Language:Inglês
Published: MDPI 2019
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912470/
https://ncbi.nlm.nih.gov/pubmed/31739555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111438
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