The Circulating GRP78/BiP Is a Marker of Metabolic Diseases and Atherosclerosis: Bringing Endoplasmic Reticulum Stress into the Clinical Scenario

Background: Glucose-regulated protein 78/Binding immunoglobulin protein (GRP78/BiP) is a protein associated with endoplasmic reticulum stress and is upregulated by metabolic alterations at the tissue-level, such as hypoxia or glucose deprivation, and it is hyper-expressed in fat tissue of obese indi...

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Veröffentlicht in:J Clin Med
Hauptverfasser: Girona, Josefa, Rodríguez-Borjabad, Cèlia, Ibarretxe, Daiana, Vallvé, Joan-Carles, Ferré, Raimon, Heras, Mercedes, Rodríguez-Calvo, Ricardo, Guaita-Esteruelas, Sandra, Martínez-Micaelo, Neus, Plana, Núria, Masana, Lluís
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912434/
https://ncbi.nlm.nih.gov/pubmed/31717752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8111793
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