Evaluating the Intactness of Persistent Viral Genomes in Simian Immunodeficiency Virus-Infected Rhesus Macaques after Initiating Antiretroviral Therapy within One Year of Infection

The major obstacle to more-definitive treatment for HIV infection is the early establishment of virus that persists despite long-term combination antiretroviral therapy (cART) and can cause recrudescent viremia if cART is interrupted. Previous studies of HIV DNA that persists despite cART indicated...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Long, Samuel, Fennessey, Christine M., Newman, Laura, Reid, Carolyn, O’Brien, Sean P., Li, Yuan, Del Prete, Gregory Q., Lifson, Jeffrey D., Gorelick, Robert J., Keele, Brandon F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912123/
https://ncbi.nlm.nih.gov/pubmed/31597776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01308-19
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