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LIN28A loss of function is associated with Parkinson's disease pathogenesis

Parkinson's disease (PD) is neurodegenerative movement disorder characterized by degeneration of midbrain‐type dopamine (mDA) neurons in the substantia nigra (SN). The RNA‐binding protein Lin28 plays a role in neuronal stem cell development and neuronal differentiation. In this study, we reveal...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Chang, Mi‐Yoon, Oh, Boram, Choi, Jang‐Eun, Sulistio, Yanuar Alan, Woo, Hye‐Ji, Jo, Ayoung, Kim, Jinil, Kim, Eun‐Hee, Kim, Seung Won, Hwang, Jungwook, Park, Jungyun, Song, Jae‐Jin, Kwon, Oh‐Chan, Henry Kim, Hyongbum, Kim, Young‐Hoon, Ko, Joo Yeon, Heo, Jun Young, Lee, Min Joung, Lee, Moses, Choi, Murim, Chung, Sun Ju, Lee, Hyun‐Seob, Lee, Sang‐Hun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912061/
https://ncbi.nlm.nih.gov/pubmed/31750563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101196
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