TAE226, a dual inhibitor of focal adhesion kinase and insulin‐like growth factor‐I receptor, is effective for Ewing sarcoma

The outcomes for relapsed and metastatic Ewing sarcoma (EWS) is extremely poor. Therefore, it is important to identify the tumor‐specific targets in these intractable diseases. High focal adhesion kinase (FAK) transcript expression levels in EWS cell lines are known. TAE226 is a dual inhibitor of FA...

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Foilsithe in:Cancer Med
Main Authors: Moritake, Hiroshi, Saito, Yusuke, Sawa, Daisuke, Sameshima, Naoki, Yamada, Ai, Kinoshita, Mariko, Kamimura, Sachiyo, Konomoto, Takao, Nunoi, Hiroyuki
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
Ábhair:
Cancer Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912025/
https://ncbi.nlm.nih.gov/pubmed/31692287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2647
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