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20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis

BACKGROUND: Cancer stem cells (CSCs) have been proposed as central drivers of cancer relapse in many cancers. In the present study, we investigated the inhibitory effect of 20(R)-Ginsenoside Rg3 (Rg3R), a major active component of ginseng saponin, on CSC-like cells and the Epithelial-Mesenchymal Tra...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Phi, Lan Thi Hanh, Wijaya, Yoseph Toni, Sari, Ita Novita, Kim, Kwang Seock, Yang, Ying-Gui, Lee, Min-Woo, Kwon, Hyog Young
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912006/
https://ncbi.nlm.nih.gov/pubmed/31849492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S219063
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