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Suppression of HIF2 signaling attenuates the initiation of hypoxia-induced pulmonary hypertension

Most published studies addressing the role of HIFs in hypoxia-induced PH development employ models that may not recapitulate the clinical setting, including the use of animals having pre-existing lung/vascular defects secondary to embryonic HIF ablation or activation. Further, critical questions inc...

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書誌詳細
出版年:Eur Respir J
主要な著者: Hu, Cheng-Jun, Poth, Jens M., Zhang, Hui, Flockton, Amanda, Laux, Aya, Kumar, Sushil, McKeon, Brittany, Frid, Maria G., Mouradian, Gary, Li, Min, Riddle, Suzette, Pugliese, Steven C., Brown, R. Dale, Wallace, Eli M., Graham, Brian B., Stenmark, Kurt R.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911916/
https://ncbi.nlm.nih.gov/pubmed/31515405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00378-2019
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