Suppression of HIF2 signaling attenuates the initiation of hypoxia-induced pulmonary hypertension

Most published studies addressing the role of HIFs in hypoxia-induced PH development employ models that may not recapitulate the clinical setting, including the use of animals having pre-existing lung/vascular defects secondary to embryonic HIF ablation or activation. Further, critical questions inc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Eur Respir J
Päätekijät: Hu, Cheng-Jun, Poth, Jens M., Zhang, Hui, Flockton, Amanda, Laux, Aya, Kumar, Sushil, McKeon, Brittany, Frid, Maria G., Mouradian, Gary, Li, Min, Riddle, Suzette, Pugliese, Steven C., Brown, R. Dale, Wallace, Eli M., Graham, Brian B., Stenmark, Kurt R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911916/
https://ncbi.nlm.nih.gov/pubmed/31515405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.00378-2019
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