Cell-Type-Specific Complement Expression in the Healthy and Diseased Retina

Complement dysregulation is a feature of many retinal diseases, yet mechanistic understanding at the cellular level is limited. Given this knowledge gap about which retinal cells express complement, we performed single-cell RNA sequencing on ~92,000 mouse retinal cells and validated our results in f...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Pauly, Diana, Agarwal, Divyansh, Dana, Nicholas, Schäfer, Nicole, Biber, Josef, Wunderlich, Kirsten A., Jabri, Yassin, Straub, Tobias, Zhang, Nancy R., Gautam, Avneesh K., Weber, Bernhard H.F., Hauck, Stefanie M., Kim, Mijin, Curcio, Christine A., Stambolian, Dwight, Li, Mingyao, Grosche, Antje
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911814/
https://ncbi.nlm.nih.gov/pubmed/31775049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.084
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