Pharmacological Evaluation of Aldehydic-Pyrrolidinedione Against HCT-116, MDA-MB231, NIH/3T3, MCF-7 Cancer Cell Lines, Antioxidant and Enzyme Inhibition Studies

PURPOSE: The current work was designed to synthesize a bioactive derivative of succinimide and evaluate it for anti-Alzheimer, anticancer and anti-diabetic potentials. METHODS: The compound was synthesized by Michael addition of butyraldehyde with N-phenylmaleimide. The synthesized compound was scre...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ahmad, Ashfaq, Ullah, Farhat, Sadiq, Abdul, Ayaz, Muhammad, Rahim, Haroon, Rashid, Umer, Ahmad, Sajjad, Jan, Muhammad Saeed, Ullah, Riaz, Shahat, Abdelaaty A, Mahmood, Hafiz Majid
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911349/
https://ncbi.nlm.nih.gov/pubmed/31849450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S226080
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