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A universal transportin protein drives stochastic choice of olfactory neurons via specific nuclear import of a sox-2-activating factor

Stochastic neuronal cell fate choice involving notch-independent mechanisms is a poorly understood biological process. The Caenorhabditis elegans AWC olfactory neuron pair asymmetrically differentiates into the default AWC(OFF) and induced AWC(ON) subtypes in a stochastic manner. Stochastic choice o...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Alqadah, Amel, Hsieh, Yi-Wen, Xiong, Rui, Lesch, Bluma J., Chang, Chieh, Chuang, Chiou-Fen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911211/
https://ncbi.nlm.nih.gov/pubmed/31767767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908168116
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