Molecular basis of arrhythmic substrate in ageing murine peroxisome proliferator-activated receptor γ co-activator deficient hearts modelling mitochondrial dysfunction

Introduction: Ageing and chronic metabolic disorders are associated with mitochondrial dysfunction and cardiac pro-arrhythmic phenotypes which were recently attributed to slowed atrial and ventricular action potential (AP) conduction in peroxisome proliferator-activated receptor γ co-activator defic...

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Enregistré dans:
Détails bibliographiques
Publié dans:Biosci Rep
Auteurs principaux: Edling, Charlotte E., Fazmin, Ibrahim T., Saadeh, Khalil, Chadda, Karan R., Ahmad, Shiraz, Valli, Haseeb, Huang, Christopher L.-H., Jeevaratnam, Kamalan
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2019
Sujets:
Aging
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911157/
https://ncbi.nlm.nih.gov/pubmed/31778152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190403
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