Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients

In order to improve targeted therapeutic approaches for asthma patients, insights into the molecular mechanisms that differentially contribute to disease phenotypes, such as obese asthmatics or severe asthmatics, are required. Here we report immunological and microbiome alterations in obese asthmati...

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Vydáno v:Nat Commun
Hlavní autoři: Michalovich, David, Rodriguez-Perez, Noelia, Smolinska, Sylwia, Pirozynski, Michal, Mayhew, David, Uddin, Sorif, Van Horn, Stephanie, Sokolowska, Milena, Altunbulakli, Can, Eljaszewicz, Andrzej, Pugin, Benoit, Barcik, Weronika, Kurnik-Lucka, Magdalena, Saunders, Ken A., Simpson, Karen D., Schmid-Grendelmeier, Peter, Ferstl, Ruth, Frei, Remo, Sievi, Noriane, Kohler, Malcolm, Gajdanowicz, Pawel, Graversen, Katrine B., Lindholm Bøgh, Katrine, Jutel, Marek, Brown, James R., Akdis, Cezmi A., Hessel, Edith M., O’Mahony, Liam
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6911092/
https://ncbi.nlm.nih.gov/pubmed/31836714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13751-9
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