Routine free thyroxine reference intervals are suboptimal for monitoring children on thyroxine replacement therapy and target intervals need to be assay-specific

Central hypothyroidism is a condition where there is (qualitatively or quantitatively) TSH deficiency, leading to reduced thyroid hormone production. In such patients, serum TSH does not accurately reflect the adequacy of thyroxine replacement, as the log-linear relationship between thyrotropin (TSH...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wheeler, Elizabeth, Choy, Kay Weng, Chin, Lit Kim, Wijeratne, Nilika, McNeil, Alan, Yen, Tina, Matthews, Susan, Deam, David, Lu, Zhong, Loh, Tze Ping, Doery, James, Bergman, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910984/
https://ncbi.nlm.nih.gov/pubmed/31836869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55690-x
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