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Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS

Carboxyl-containing metabolites, such as bile acids and fatty acids, have many important functions and microbiota is involved in the production of them. In the previous study, we found that the chronic kidney disease (CKD) model mice raised under germ-free conditions provided more severe renal damag...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kanemitsu, Yoshitomi, Mishima, Eikan, Maekawa, Masamitsu, Matsumoto, Yotaro, Saigusa, Daisuke, Yamaguchi, Hiroaki, Ogura, Jiro, Tsukamoto, Hiroki, Tomioka, Yoshihisa, Abe, Takaaki, Mano, Nariyasu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910927/
https://ncbi.nlm.nih.gov/pubmed/31836785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55600-1
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