Live-Attenuated Influenza Vaccine Induces Tonsillar Follicular T Helper Cell Responses That Correlate With Antibody Induction

BACKGROUND: Influenza remains a major threat to public health. Live-attenuated influenza vaccines (LAIV) have been shown to be effective, particularly in children. Follicular T helper (TFH) cells provide B-cell help and are crucial for generating long-term humoral immunity. However the role of TFH c...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Lartey, Sarah, Zhou, Fan, Brokstad, Karl A, Mohn, Kristin G-I, Slettevoll, Steffen A, Pathirana, Rishi D, Cox, Rebecca J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910880/
https://ncbi.nlm.nih.gov/pubmed/31250024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz321
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