Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation

BACKGROUND: Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory CD4(+)F...

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Udgivet i:J Infect Dis
Main Authors: Attaher, Oumar, Zaidi, Irfan, Kwan, Jennifer L, Issiaka, Djibrilla, Samassekou, Mamoudou B, Cisse, Kadidia B, Coulibaly, Barou, Keita, Sekouba, Sissoko, Sibiri, Traore, Tiangoua, Diarra, Kalifa, Diarra, Bacary S, Dembele, Adama, Kanoute, Moussa B, Mahamar, Almahamoudou, Barry, Amadou, Fried, Michal, Dicko, Alassane, Duffy, Patrick E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910875/
https://ncbi.nlm.nih.gov/pubmed/31584094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz415
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