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Topology-dependent anomalous dynamics of ring and linear DNA are sensitive to cytoskeleton crosslinking

Cytoskeletal crowding plays a key role in the diffusion of DNA molecules through the cell, acting as a barrier to effective intracellular transport and conformational stability required for processes such as transfection, viral infection, and gene therapy. Here, we elucidate the transport properties...

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Detalles Bibliográficos
Publicado en:Sci Adv
Autores principales: Wulstein, Devynn M., Regan, Kathryn E., Garamella, Jonathan, McGorty, Ryan J., Robertson-Anderson, Rae M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Association for the Advancement of Science 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910835/
https://ncbi.nlm.nih.gov/pubmed/31853502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay5912
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