Agonist of PPAR-γ Reduced Epithelial-Mesenchymal Transition in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps via Inhibition of High Mobility Group Box1

Epithelial-mesenchymal transition (EMT) has been reported to occur in eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). Among the cytokines that cause EMT, high mobility group box 1 (HMGB1) has been shown to give rise to EMT in airway epithelial cells. However, the mechanism of HMGB1-...

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Bibliographic Details
Published in:Int J Med Sci
Main Authors: Yang, Pingli, Chen, Shan, Zhong, Gang, Kong, Weijia, Wang, Yanjun
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909805/
https://ncbi.nlm.nih.gov/pubmed/31839751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.35936
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