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Angiogenic inflammation and formation of necrosis in the tumor microenvironment influence patient survival after radical surgery for de novo hepatocellular carcinoma in non-cirrhosis

BACKGROUND: Tumor escape mechanisms mediated in the tumor microenvironment can significantly reduce the capacity of the anti-tumor function of the immune system. TIE2-expressing monocytes (TEMs), related angiopoietins, and tumor necrosis are considered to have a key role in this process. We aimed to...

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Publicado en:World J Surg Oncol
Autores principales: Atanasov, Georgi, Dino, Karoline, Schierle, Katrin, Dietel, Corinna, Aust, Gabriela, Pratschke, Johann, Seehofer, Daniel, Schmelzle, Moritz, Hau, Hans-Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909650/
https://ncbi.nlm.nih.gov/pubmed/31830991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-019-1756-8
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