Ischemia reperfusion injury promotes recurrence of hepatocellular carcinoma in fatty liver via ALOX12-12HETE-GPR31 signaling axis

BACKGROUND: Ischemia reperfusion injury (IRI) has been shown to increase the risk of tumor recurrence after liver surgery. Also, nonalcoholic fatty liver disease (NAFLD) is associated with increased HCC recurrence. ALOX12–12-HETE pathway is activated both in liver IRI and NASH. Also, ALOX12–12-HETE...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yang, Faji, Zhang, Yuheng, Ren, Haozhen, Wang, Jinglin, Shang, Longcheng, Liu, Yang, Zhu, Wei, Shi, Xiaolei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909624/
https://ncbi.nlm.nih.gov/pubmed/31831037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1480-9
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