SATB1 establishes ameloblast cell polarity and regulates directional amelogenin secretion for enamel formation

BACKGROUND: Polarity is necessary for epithelial cells to perform distinct functions at their apical and basal surfaces. Oral epithelial cell-derived ameloblasts at secretory stage (SABs) synthesize large amounts of enamel matrix proteins (EMPs), largely amelogenins. EMPs are unidirectionally secret...

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Détails bibliographiques
Publié dans:BMC Biol
Auteurs principaux: Zhang, Yan, Zheng, Liwei, Le, Michael, Nakano, Yukiko, Chan, Barry, Huang, Yulei, Torbaty, Parisa Moravedje, Kohwi, Yoshinori, Marcucio, Ralph, Habelitz, Stefan, Den Besten, Pamela K., Kohwi-Shigematsu, Terumi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909472/
https://ncbi.nlm.nih.gov/pubmed/31830989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0722-9
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