Targeting of the Eukaryotic Translation Initiation Factor 4A Against Breast Cancer Stemness

Breast cancer stem cells (BCSCs) are intrinsically chemoresistant and capable of self-renewal. Following chemotherapy, patients can develop minimal residual disease due to BCSCs which can repopulate into a relapsed tumor. Therefore, it is imperative to co-target BCSCs along with the bulk tumor cells...

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Dettagli Bibliografici
Pubblicato in:Front Oncol
Autori principali: Sridharan, Sangita, Robeson, Megan, Bastihalli-Tukaramrao, Diwakar, Howard, Cory M., Subramaniyan, Boopathi, Tilley, Augustus M. C., Tiwari, Amit K., Raman, Dayanidhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909344/
https://ncbi.nlm.nih.gov/pubmed/31867270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01311
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