Divergent Roles of Kupffer Cell TLR2/3 Signaling in Alcoholic Liver Disease and the Protective Role of EGCG

BACKGROUND & AIMS: Toll-like receptor 2 (TLR2) and TLR3 regulate hepatic immunity under pathological conditions, but their functions and potential drug targets in alcoholic liver disease (ALD) remain poorly understood. METHODS: ALD-associated liver injury were induced in TLR2 knockout (TLR2(–/–)...

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Опубликовано в: :Cell Mol Gastroenterol Hepatol
Главные авторы: Luo, Pingping, Wang, Fei, Wong, Nai-Kei, Lv, Yi, Li, Xinxin, Li, Mianhuan, Tipoe, George L., So, Kwok-Fai, Xu, Aimin, Chen, Shuaiyin, Xiao, Jia, Wang, Hua
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6909006/
https://ncbi.nlm.nih.gov/pubmed/31562937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.09.002
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