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Plasmid-based and -free methods using CRISPR/Cas9 system for replacement of targeted genes in Colletotrichum sansevieriae

The CRISPR-Cas9 system has a potential for wide application in organisms that particularly present low homologous integration rates. In this study, we developed three different methods using this system to replace a gene through homology-directed repair in the plant pathogenic fungus Colletotrichum...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakamura, Masayuki, Okamura, Yuta, Iwai, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908651/
https://ncbi.nlm.nih.gov/pubmed/31831810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55302-8
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