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ERK1/2 drives IL-1β-induced expression of TGF-β1 and BMP-2 in torn tendons
Diseased and injured tendons develop fibrosis, driven by factors including TGF-β, BMPs and CTGF. IL-1β and its signal transducer Erk1/2 are known to regulate TGF-β expression in animal tendons. We utilised tissues and cells isolated from patients with shoulder tendon tears and tendons of healthy vol...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6908634/ https://ncbi.nlm.nih.gov/pubmed/31831776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55387-1 |
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