Ibrutinib–Rituximab or Chemoimmunotherapy for Chronic Lymphocytic Leukemia

BACKGROUND: Data regarding the efficacy of treatment with ibrutinib–rituximab, as compared with standard chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab, in patients with previously untreated chronic lymphocytic leukemia (CLL) have been limited. METHODS: In a phase 3 trial, we r...

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Publicado en:N Engl J Med
Autores principales: Shanafelt, Tait D., Wang, Xin V., Kay, Neil E., Hanson, Curtis A., O’Brien, Susan, Barrientos, Jacqueline, Jelinek, Diane F., Braggio, Esteban, Leis, Jose F., Zhang, Cong C., Coutre, Steven E., Barr, Paul M., Cashen, Amanda F., Mato, Anthony R., Singh, Avina K., Mullane, Michael P., Little, Richard F., Erba, Harry, Stone, Richard M., Litzow, Mark, Tallman, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6908306/
https://ncbi.nlm.nih.gov/pubmed/31365801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1817073
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