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Escherichia coli “TatExpress” strains export several g/L human growth hormone to the periplasm by the Tat pathway

Escherichia coli is a heavily used platform for the production of biotherapeutic and other high‐value proteins, and a favored strategy is to export the protein of interest to the periplasm to simplify downstream processing and facilitate disulfide bond formation. The Sec pathway is the standard mean...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Guerrero Montero, Isabel, Richards, Kirsty L., Jawara, Chillel, Browning, Douglas F., Peswani, Amber R., Labrit, Mickael, Allen, Matthew, Aubry, Cedric, Davé, Emma, Humphreys, David P., Busby, Stephen J. W., Robinson, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907408/
https://ncbi.nlm.nih.gov/pubmed/31429928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27147
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