PI3K/Akt inhibitor partly decreases TNF-α-induced activation of fibroblast-like synoviocytes in osteoarthritis

BACKGROUND: The Cadherin-11 and PI3K/Akt pathway are increasingly recognized as the potential therapeutic target of osteoarthritis (OA) synovitis. The study aimed to investigate the role of PI3K/Akt signaling pathway in the expression of Cadherin-11 and migration and invasive capacity of fibroblast-...

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Bibliografiska uppgifter
I publikationen:J Orthop Surg Res
Huvudupphovsmän: Liu, Songyang, Cao, Chenxi, Zhang, Yujun, Liu, Guangyu, Ren, Weixia, Ye, Yanqi, Sun, Tiezheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907257/
https://ncbi.nlm.nih.gov/pubmed/31829201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-019-1394-4
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