Germline POLE and POLD1 proofreading domain mutations in endometrial carcinoma from Middle Eastern region

BACKGROUND: Endometrial carcinoma (EC) accounts for 5.8% of all cancers in Saudi females. Although most ECs are sporadic, 2–5% tend to be familial, being associated with Lynch syndrome and Cowden syndrome. In this study, we attempted to uncover the frequency, spectrum and phenotype of germline mutat...

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Bibliografski detalji
Izdano u:Cancer Cell Int
Glavni autori: Siraj, Abdul K., Parvathareddy, Sandeep Kumar, Bu, Rong, Iqbal, Kaleem, Siraj, Sarah, Masoodi, Tariq, Concepcion, Rica Micaela, Ghazwani, Laila Omar, AlBadawi, Ismail, Al-Dayel, Fouad, Al-Kuraya, Khawla S.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Primary Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907229/
https://ncbi.nlm.nih.gov/pubmed/31866764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-1058-9
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