Pioglitazone prevents cholesterol gallstone formation through the regulation of cholesterol homeostasis in guinea pigs with a lithogenic diet

BACKGROUND: The cholesterol gallstones diseases (CGD) is highly correlated with metabolic syndrome and type 2 diabetes. The present study aimed to investigate preventive effects of pioglitazone (PIO), an antidiabetic drug, on the CGD in guinea pigs fed with a lithogenic diet (LD). METHODS: The guine...

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Veröffentlicht in:Lipids Health Dis
Hauptverfasser: Han, Tao, Lv, Yangge, Wang, Shijia, Hu, Tao, Hong, Hao, Fu, Zan
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907187/
https://ncbi.nlm.nih.gov/pubmed/31829191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-019-1159-4
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