The Herb-Drug Pharmacokinetic Interaction of Fluoxetine and Its Metabolite Norfluoxetine with a Traditional Chinese Medicine in Rats by LC-MS/MS

BACKGROUND: Fluoxetine (FLU) is the first-line and widely used medication for depression. The combination of Chaihu Shugan san (CSGS) and FLU is commonly used to enhance antidepressant effects and reduce side effects. OBJECTIVE: The primary objective of this study was to investigate the potential ph...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Principais autores: Yan, Lijing, Wang, Sheng, Zhao, Linlin, Qiu, Juan, Zhou, Lu, Wang, Wenbo, Xu, Xia, Wang, Dongsheng, Qiu, Xinjian, Qin, Dilan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6907063/
https://ncbi.nlm.nih.gov/pubmed/31871472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2471870
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