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Quantification of d-Ala-d-Lac terminated peptidoglycan structure in vancomycin-resistant Enterococcus faecalis using a combined solid-state NMR and mass spectrometry analysis

Induction of vancomycin resistance in vancomycin-resistant enterococci (VRE) involves replacement of the d-Ala-d-Ala terminus of peptidoglycan (PG) stems with d-Ala-d-Lac, dramatically reducing the binding affinity of vancomycin to lipid II. Effects from vancomycin resistance induction on Enterococc...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Chang, James D., Foster, Erin E., Yang, Hao, Kim, Sung Joon
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906607/
https://ncbi.nlm.nih.gov/pubmed/28040891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00774
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