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Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues

The vaginal microbiota, dominated by Lactobacillus spp., plays a key role in preventing HIV-1 transmission. Here, we investigate whether the anti-HIV effect of lactobacilli is mediated by extracellular vesicles (EVs) released by these bacteria. Human cervico-vaginal and tonsillar tissues ex vivo, an...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ñahui Palomino, Rogers A., Vanpouille, Christophe, Laghi, Luca, Parolin, Carola, Melikov, Kamran, Backlund, Peter, Vitali, Beatrice, Margolis, Leonid
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906448/
https://ncbi.nlm.nih.gov/pubmed/31827089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13468-9
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