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Limited antibody specificity compromises epitranscriptomic analyses

A controversial discussion on the occurrence of the RNA modification m(1)A in mRNA takes a new turn, as an antibody with a central role in modification mapping was shown to also bind mRNA cap structures.

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Helm, Mark, Lyko, Frank, Motorin, Yuri
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906430/
https://ncbi.nlm.nih.gov/pubmed/31827101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13684-3
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