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Transcriptional and Translational Inhibitors Block SOS Response and Shiga Toxin Expression in Enterohemorrhagic Escherichia coli

Shiga toxins (Stx) induce the symptoms of the life-threatening hemolytic uremic syndrome (HUS) and are the main virulence factors of enterohemorrhagic Escherichia coli (EHEC). The bacterial SOS response is the essential signal for high level production and release of Stx1/2. To assess the potential...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Berger, Michael, Aijaz, Iqbal, Berger, Petya, Dobrindt, Ulrich, Koudelka, Gerald
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906329/
https://ncbi.nlm.nih.gov/pubmed/31827185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55332-2
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