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Transcriptional and Translational Inhibitors Block SOS Response and Shiga Toxin Expression in Enterohemorrhagic Escherichia coli

Shiga toxins (Stx) induce the symptoms of the life-threatening hemolytic uremic syndrome (HUS) and are the main virulence factors of enterohemorrhagic Escherichia coli (EHEC). The bacterial SOS response is the essential signal for high level production and release of Stx1/2. To assess the potential...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Berger, Michael, Aijaz, Iqbal, Berger, Petya, Dobrindt, Ulrich, Koudelka, Gerald
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906329/
https://ncbi.nlm.nih.gov/pubmed/31827185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55332-2
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