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Polymorphism in the LASP1 gene promoter region alters cognitive functions of patients with schizophrenia

Schizophrenia’s pathogenesis remains elusive. Cognitive dysfunction is the endophenotype and outcome predictor of schizophrenia. The LIM and SH3 domain protein (LASP1) protein, a component of CNS synapses and dendritic spines, has been related to the N-methyl-D-aspartate receptor (NMDAR) dysfunction...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Lin, Chieh-Hsin, Yang, Sheng, Huang, Yu-Jhen, Lane, Hsien-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906281/
https://ncbi.nlm.nih.gov/pubmed/31827227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55414-1
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